Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, Lausanne, Switzerland. Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, Lausanne, Switzerland. ping-chih.ho@unil.ch. Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. c.mauro@bham.ac.uk. Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. c.mauro@bham.ac.uk. Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. c.mauro@bham.ac.uk.